There are
1,644 mi
from Yankton, SD to Manteca, CA
That's the driving distance. It would take 1 day 4 hours to go from Yankton, South Dakota to Manteca, California.
The flight distance (direct flight from Yankton, SD to Manteca, CA) is 1,297.63 mi.
1,644 mi = 2,645.51 kms