There are
1,109 mi
from Yankton, SD to Laurel, MS
That's the driving distance. It would take 20 hours 41 mins to go from Yankton, South Dakota to Laurel, Mississippi.
The flight distance (direct flight from Yankton, SD to Laurel, MS) is 894.98 mi.
1,109 mi = 1,784.37 kms