There are
1,252 mi
from Yankton, SD to Ithaca, NY
That's the driving distance. It would take 23 hours 23 mins to go from Yankton, South Dakota to Ithaca, New York.
The flight distance (direct flight from Yankton, SD to Ithaca, NY) is 1,059.43 mi.
1,252 mi = 2,015.28 kms