There are
1,502 mi
from Wilmington, NC to Sioux Falls, SD
That's the driving distance. It would take 1 day 3 hours to go from Wilmington, North Carolina to Sioux Falls, South Dakota.
The flight distance (direct flight from Wilmington, NC to Sioux Falls, SD) is 1,192.59 mi.
1,502 mi = 1.61 kms