There are
670 mi
from Wilmington, NC to Poughkeepsie, NY
That's the driving distance. It would take 13 hours 12 mins to go from Wilmington, North Carolina to Poughkeepsie, New York.
The flight distance (direct flight from Wilmington, NC to Poughkeepsie, NY) is 560.86 mi.
670 mi = 1,078.61 kms