There are
197 mi
from Wilmington, DE to Poughkeepsie, NY
That's the driving distance. It would take 4 hours 8 mins to go from Wilmington, Delaware to Poughkeepsie, New York.
The flight distance (direct flight from Wilmington, DE to Poughkeepsie, NY) is 159.63 mi.
197 mi = 317.31 kms