Miles between Wilmington, DE and Lancaster, SC

There are
544 mi
from Wilmington, DE to Lancaster, SC

That's the driving distance. It would take 10 hours 48 mins to go from Wilmington, Delaware to Lancaster, South Carolina.

The flight distance (direct flight from Wilmington, DE to Lancaster, SC) is 450.54 mi.

544 mi = 876.25 kms