Miles between Wilmington, DE and Charleston, SC

There are
645 mi
from Wilmington, DE to Charleston, SC

That's the driving distance. It would take 12 hours 18 mins to go from Wilmington, Delaware to Charleston, South Carolina.

The flight distance (direct flight from Wilmington, DE to Charleston, SC) is 539.74 mi.

645 mi = 1,037.56 kms