There are
1,354 mi
from West Columbia, SC to Lexington, NE
That's the driving distance. It would take 1 day 1 hour to go from West Columbia, South Carolina to Lexington, Nebraska.
The flight distance (direct flight from West Columbia, SC to Lexington, NE) is 1,123.81 mi.
1,354 mi = 2,178.80 kms