There are
485 mi
from West Allis, WI to Sikeston, MO
That's the driving distance. It would take 9 hours 5 mins to go from West Allis, Wisconsin to Sikeston, Missouri.
The flight distance (direct flight from West Allis, WI to Sikeston, MO) is 432.39 mi.
485 mi = 780.45 kms