There are
1,375 mi
from Waterloo, IA to Weslaco, TX
That's the driving distance. It would take 1 day to go from Waterloo, Iowa to Weslaco, Texas.
The flight distance (direct flight from Waterloo, IA to Weslaco, TX) is 1,172.90 mi.
1,375 mi = 2,212.67 kms