There are
1,206 mi
from Waterbury, CT to Kirksville, MO
That's the driving distance. It would take 22 hours 41 mins to go from Waterbury, Connecticut to Kirksville, Missouri.
The flight distance (direct flight from Waterbury, CT to Kirksville, MO) is 1,022.54 mi.
1,206 mi = 1.61 kms