There are
301 mi
from Vacaville, CA to Klamath Falls, OR
That's the driving distance. It would take 5 hours 37 mins to go from Vacaville, California to Klamath Falls, Oregon.
The flight distance (direct flight from Vacaville, CA to Klamath Falls, OR) is 267.49 mi.
301 mi = 485.15 kms