There are
1,539 mi
from Upland, CA to Vermillion, SD
That's the driving distance. It would take 1 day 3 hours to go from Upland, California to Vermillion, South Dakota.
The flight distance (direct flight from Upland, CA to Vermillion, SD) is 1,266.81 mi.
1,539 mi = 2,477.24 kms