There are
2,341 mi
from Upland, CA to Lexington, SC
That's the driving distance. It would take 1 day 17 hours to go from Upland, California to Lexington, South Carolina.
The flight distance (direct flight from Upland, CA to Lexington, SC) is 2,073.46 mi.
2,341 mi = 3.22 kms