There are
2,861 mi
from Upland, CA to Holyoke, MA
That's the driving distance. It would take 2 days 3 hours to go from Upland, California to Holyoke, Massachusetts.
The flight distance (direct flight from Upland, CA to Holyoke, MA) is 2,480.03 mi.
2,861 mi = 3.22 kms