There are
370 mi
from Tuscaloosa, AL to Waynesville, NC
That's the driving distance. It would take 7 hours 15 mins to go from Tuscaloosa, Alabama to Waynesville, North Carolina.
The flight distance (direct flight from Tuscaloosa, AL to Waynesville, NC) is 305.01 mi.
370 mi = 595.36 kms