There are
2,280 mi
from Tuscaloosa, AL to Santa Cruz, CA
That's the driving distance. It would take 1 day 16 hours to go from Tuscaloosa, Alabama to Santa Cruz, California.
The flight distance (direct flight from Tuscaloosa, AL to Santa Cruz, CA) is 1,954.84 mi.
2,280 mi = 3,670.00 kms