There are
557 mi
from Tuscaloosa, AL to Reidsville, NC
That's the driving distance. It would take 10 hours 32 mins to go from Tuscaloosa, Alabama to Reidsville, North Carolina.
The flight distance (direct flight from Tuscaloosa, AL to Reidsville, NC) is 498.21 mi.
557 mi = 896.68 kms