There are
518 mi
from Tuscaloosa, AL to Chesterfield, MO
That's the driving distance. It would take 9 hours 45 mins to go from Tuscaloosa, Alabama to Chesterfield, Missouri.
The flight distance (direct flight from Tuscaloosa, AL to Chesterfield, MO) is 412.58 mi.
518 mi = 833.46 kms