There are
515 mi
from Topeka, KS to Owensboro, KY
That's the driving distance. It would take 9 hours 46 mins to go from Topeka, Kansas to Owensboro, Kentucky.
The flight distance (direct flight from Topeka, KS to Owensboro, KY) is 472.59 mi.
515 mi = 828.58 kms