There are
1,206 mi
from Topeka, KS to Mesquite, NV
That's the driving distance. It would take 20 hours 32 mins to go from Topeka, Kansas to Mesquite, Nevada.
The flight distance (direct flight from Topeka, KS to Mesquite, NV) is 1,011.76 mi.
1,206 mi = 1.61 kms