There are
1,064 mi
from Topeka, KS to Lexington, SC
That's the driving distance. It would take 19 hours 43 mins to go from Topeka, Kansas to Lexington, South Carolina.
The flight distance (direct flight from Topeka, KS to Lexington, SC) is 874.44 mi.
1,064 mi = 1.61 kms