There are
2,013 mi
from Thousand Oaks, CA to St Charles, IL
That's the driving distance. It would take 1 day 11 hours to go from Thousand Oaks, California to St Charles, Illinois.
The flight distance (direct flight from Thousand Oaks, CA to St Charles, IL) is 1,734.53 mi.
2,013 mi = 3.22 kms