There are
2,475 mi
from Thousand Oaks, CA to Lexington, NC
That's the driving distance. It would take 1 day 19 hours to go from Thousand Oaks, California to Lexington, North Carolina.
The flight distance (direct flight from Thousand Oaks, CA to Lexington, NC) is 2,172.73 mi.
2,475 mi = 3.22 kms