There are
2,687 mi
from Thousand Oaks, CA to Ephrata, PA
That's the driving distance. It would take 2 days to go from Thousand Oaks, California to Ephrata, Pennsylvania.
The flight distance (direct flight from Thousand Oaks, CA to Ephrata, PA) is 2,361.85 mi.
2,687 mi = 3.22 kms