There are
2,599 mi
from Thousand Oaks, CA to Clayton, NC
That's the driving distance. It would take 1 day 21 hours to go from Thousand Oaks, California to Clayton, North Carolina.
The flight distance (direct flight from Thousand Oaks, CA to Clayton, NC) is 2,274.14 mi.
2,599 mi = 4,183.25 kms