There are
1,725 mi
from Temecula, CA to Opelousas, LA
That's the driving distance. It would take 1 day 5 hours to go from Temecula, California to Opelousas, Louisiana.
The flight distance (direct flight from Temecula, CA to Opelousas, LA) is 1,479.06 mi.
1,725 mi = 1.61 kms