There are
1,344 mi
from Tallahassee, FL to Sioux Falls, SD
That's the driving distance. It would take 1 day 1 hour to go from Tallahassee, Florida to Sioux Falls, South Dakota.
The flight distance (direct flight from Tallahassee, FL to Sioux Falls, SD) is 1,133.23 mi.
1,344 mi = 2,162.58 kms