There are
2,841 mi
from St Petersburg, FL to San Mateo, CA
That's the driving distance. It would take 2 days 3 hours to go from St Petersburg, Florida to San Mateo, California.
The flight distance (direct flight from St Petersburg, FL to San Mateo, CA) is 2,385.91 mi.
2,841 mi = 4,572.79 kms