Miles between St Louis, MO and Picayune, MS

There are
639 mi
from St Louis, MO to Picayune, MS

That's the driving distance. It would take 11 hours 47 mins to go from St Louis, Missouri to Picayune, Mississippi.

The flight distance (direct flight from St Louis, MO to Picayune, MS) is 560.54 mi.

639 mi = 1,027.76 kms