Miles between St Louis, MO and Middletown, OH

There are
352 mi
from St Louis, MO to Middletown, OH

That's the driving distance. It would take 6 hours 53 mins to go from St Louis, Missouri to Middletown, Ohio.

The flight distance (direct flight from St Louis, MO to Middletown, OH) is 317.11 mi.

352 mi = 565.78 kms