There are
1,969 mi
from St Louis, MO to Lompoc, CA
That's the driving distance. It would take 1 day 10 hours to go from St Louis, Missouri to Lompoc, California.
The flight distance (direct flight from St Louis, MO to Lompoc, CA) is 1,692.32 mi.
1,969 mi = 3,168.87 kms