Miles between St Louis, MO and Lancaster, SC

There are
738 mi
from St Louis, MO to Lancaster, SC

That's the driving distance. It would take 14 hours 3 mins to go from St Louis, Missouri to Lancaster, South Carolina.

The flight distance (direct flight from St Louis, MO to Lancaster, SC) is 587.67 mi.

738 mi = 1,187.60 kms