Miles between St Louis, MO and Knoxville, TN

There are
485 mi
from St Louis, MO to Knoxville, TN

That's the driving distance. It would take 8 hours 53 mins to go from St Louis, Missouri to Knoxville, Tennessee.

The flight distance (direct flight from St Louis, MO to Knoxville, TN) is 391.08 mi.

485 mi = 780.35 kms