Miles between St Louis, MO and Greenville, SC

There are
652 mi
from St Louis, MO to Greenville, SC

That's the driving distance. It would take 12 hours 20 mins to go from St Louis, Missouri to Greenville, South Carolina.

The flight distance (direct flight from St Louis, MO to Greenville, SC) is 504.48 mi.

652 mi = 1,048.55 kms