There are
1,627 mi
from St Joseph, MO to Santa Clarita, CA
That's the driving distance. It would take 1 day 4 hours to go from St Joseph, Missouri to Santa Clarita, California.
The flight distance (direct flight from St Joseph, MO to Santa Clarita, CA) is 1,353.88 mi.
1,627 mi = 1.61 kms