There are
1,769 mi
from St Joseph, MO to Issaquah, WA
That's the driving distance. It would take 1 day 6 hours to go from St Joseph, Missouri to Issaquah, Washington.
The flight distance (direct flight from St Joseph, MO to Issaquah, WA) is 1,452.64 mi.
1,769 mi = 1.61 kms