There are
684 mi
from St Joseph, MO to Chillicothe, OH
That's the driving distance. It would take 13 hours 4 mins to go from St Joseph, Missouri to Chillicothe, Ohio.
The flight distance (direct flight from St Joseph, MO to Chillicothe, OH) is 631.80 mi.
684 mi = 1,101.30 kms