There are
346 mi
from St Joseph, MO to Bettendorf, IA
That's the driving distance. It would take 6 hours 25 mins to go from St Joseph, Missouri to Bettendorf, Iowa.
The flight distance (direct flight from St Joseph, MO to Bettendorf, IA) is 260.34 mi.
346 mi = 556.90 kms