There are
1,283 mi
from St George, UT to Sioux Falls, SD
That's the driving distance. It would take 22 hours 1 min to go from St George, Utah to Sioux Falls, South Dakota.
The flight distance (direct flight from St George, UT to Sioux Falls, SD) is 992.12 mi.
1,283 mi = 1.61 kms