Miles between St Charles, MO and Lyons, IL

There are
300 mi
from St Charles, MO to Lyons, IL

That's the driving distance. It would take 5 hours 40 mins to go from St Charles, Missouri to Lyons, Illinois.

The flight distance (direct flight from St Charles, MO to Lyons, IL) is 252.60 mi.

300 mi = 482.80 kms