There are
2,007 mi
from St Charles, MO to Lathrop, CA
That's the driving distance. It would take 1 day 10 hours to go from St Charles, Missouri to Lathrop, California.
The flight distance (direct flight from St Charles, MO to Lathrop, CA) is 1,661.50 mi.
2,007 mi = 3,229.75 kms