There are
2,031 mi
from St Charles, MO to Larkspur, CA
That's the driving distance. It would take 1 day 11 hours to go from St Charles, Missouri to Larkspur, California.
The flight distance (direct flight from St Charles, MO to Larkspur, CA) is 1,727.03 mi.
2,031 mi = 3,269.02 kms