There are
1,959 mi
from St Charles, MO to Klamath Falls, OR
That's the driving distance. It would take 1 day 11 hours to go from St Charles, Missouri to Klamath Falls, Oregon.
The flight distance (direct flight from St Charles, MO to Klamath Falls, OR) is 1,650.38 mi.
1,959 mi = 3,152.13 kms