Miles between St Charles, MO and Florence, SC

There are
846 mi
from St Charles, MO to Florence, SC

That's the driving distance. It would take 15 hours 52 mins to go from St Charles, Missouri to Florence, South Carolina.

The flight distance (direct flight from St Charles, MO to Florence, SC) is 675.54 mi.

846 mi = 1,360.84 kms