There are
1,845 mi
from St Charles, MO to El Segundo, CA
That's the driving distance. It would take 1 day 8 hours to go from St Charles, Missouri to El Segundo, California.
The flight distance (direct flight from St Charles, MO to El Segundo, CA) is 1,582.23 mi.
1,845 mi = 2,969.34 kms