Miles between St Charles, MO and Columbia, SC

There are
768 mi
from St Charles, MO to Columbia, SC

That's the driving distance. It would take 14 hours 24 mins to go from St Charles, Missouri to Columbia, South Carolina.

The flight distance (direct flight from St Charles, MO to Columbia, SC) is 621.77 mi.

768 mi = 1,236.70 kms