Miles between St Charles, MO and Cape Girardeau, MO

There are
128 mi
from St Charles, MO to Cape Girardeau, MO

That's the driving distance. It would take 2 hours 28 mins to go from St Charles, Missouri to Cape Girardeau, Missouri.

The flight distance (direct flight from St Charles, MO to Cape Girardeau, MO) is 115.84 mi.

128 mi = 206.59 kms