There are
2,012 mi
from St Charles, MO to Brentwood, CA
That's the driving distance. It would take 1 day 11 hours to go from St Charles, Missouri to Brentwood, California.
The flight distance (direct flight from St Charles, MO to Brentwood, CA) is 1,682.32 mi.
2,012 mi = 3,238.10 kms